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1

The phylum Cnidaria and investigations of its toxins and venoms until 1990

Tom Turk, William R. Kem

Journal:

Year:

2009

Language:

english

File:

PDF, 261 KB

english, 2009

2

Inhibition of barnacle larval settlement and crustacean toxicity of some hoplonemertine pyridyl alkaloids

William R. Kem, Ferenc Soti, Dan Rittschof

Journal:

Biomolecular Engineering

Year:

2003

Language:

english

File:

PDF, 223 KB

english, 2003

3

Pharmacokinetic Limitations on Effects of an Alpha7-Nicotinic Receptor Agonist in Schizophrenia: Randomized Trial with an Extended-Release Formulation

Kem, William R, Olincy, Ann, Johnson, Lynn, Harris, Josette, Wagner, Brandie D, Buchanan, Robert W, Christians, Uwe, Freedman, Robert

Journal:

Neuropsychopharmacology

Year:

2018

Language:

english

File:

PDF, 214 KB

english, 2018

4

A convenient racemic synthesis of two isomeric tetrahydropyridyl alkaloids: Isoanatabine and anatabine

Anne Rouchaud, William R. Kem

Journal:

Journal of Heterocyclic Chemistry

Year:

2010

Language:

english

File:

PDF, 512 KB

english, 2010

5

Combined Portal Vein Embolization and Neoadjuvant Chemotherapy As a Treatment Strategy for Resectable Hepatic Colorectal Metastases

Covey, Anne M., Brown, Karen T., Jarnagin, William R., Brody, Lynn A., Schwartz, Lawrence, Tuorto, Scott, Sofocleous, Constantinos T., DʼAngelica, Michael, Getrajdman, George I., DeMatteo, Ronald, Kem

Journal:

Annals of Surgery

Year:

2008

Language:

english

File:

PDF, 195 KB

english, 2008

6

Clathrin-adaptor ratio and membrane tension regulate the flat-to-curved transition of the clathrin coat during endocytosis

Bucher, Delia, Frey, Felix, Sochacki, Kem A., Kummer, Susann, Bergeest, Jan-Philip, Godinez, William J., Kräusslich, Hans-Georg, Rohr, Karl, Taraska, Justin W., Schwarz, Ulrich S., Boulant, Steeve

Journal:

Nature Communications

Year:

2018

Language:

english

File:

PDF, 2.31 MB

english, 2018

7

Long-term treatment with GTS-21 or nicotine enhances water maze performance in aged rats without affecting the density of nicotinic receptor subtypes in neocortex

Kimberly B. Bjugstad, Vladimir M. Mahnir, William R. Kem, Debra J. Socci, Gary W. Arendash

Journal:

Drug Development Research

Year:

1996

Language:

english

File:

PDF, 1009 KB

english, 1996

8

ChemInform Abstract: A Convenient Racemic Synthesis of Two Isomeric Tetrahydropyridyl Alkaloids: Isoanatabine and Anatabine.

Anne Rouchaud, William R. Kem

Journal:

Year:

2010

Language:

english

File:

PDF, 35 KB

english, 2010

9

Tissue carboxylesterase activity of rainbow trout

Mace G. Barron, Kem A. Charron, William T. Stott, Stephanie E. Duvall

Journal:

Environmental Toxicology and Chemistry

Year:

1999

Language:

english

File:

PDF, 96 KB

english, 1999

10

Racemic synthesis of 2′-substituted nicotine analogs

Anne Rouchaud, William R. Kem

Journal:

Journal of Heterocyclic Chemistry

Year:

2012

Language:

english

File:

PDF, 126 KB

english, 2012

11

Hydrolysis of cholinergic anabaseine and N-methylanabaseine: Influence of cosolvents on the position of the ring-chain equilibrium—Compensatory changes

John A. Zoltewicz, Linda B. Bloom, William R. Kem

Journal:

Bioorganic Chemistry

Year:

1990

Language:

english

File:

PDF, 1.22 MB

english, 1990

12

A computational study of the binding of 3-(arylidene) anabaseines to two major brain nicotinic acetylcholine receptors and to the acetylcholine binding protein

Svetoslav H. Slavov, Maksim Radzvilovits, Susan LeFrancois, Iva B. Stoyanova-Slavova, Ferenc Soti, William R. Kem, Alan R. Katritzky

Journal:

European Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 1.51 MB

english, 2010

13

Crystal structure of human thioredoxin revealing an unraveled helix and exposed S-nitrosation site

Andrzej Weichsel, Michelle Kem, William R. Montfort

Journal:

Protein Science

Year:

2010

Language:

english

File:

PDF, 190 KB

english, 2010

14

Investigation of cytolysin variants by peptide mapping: enhanced protein characterization using complementary ionization and mass spectrometric techniques

Stanley M. Stevens Jr., William R. Kem, Laszlo Prokai

Journal:

Rapid Communications in Mass Spectrometry

Year:

2002

Language:

english

File:

PDF, 169 KB

english, 2002

15

Pyridine alkaloid distribution in the hoplonemertines

Journal:

Year:

1988

Language:

english

File:

PDF, 539 KB

english, 1988

16

Secondary structure of ShK toxin, a potassium-channel-blocking peptide

William R. Kem, Gautam Sanyal, Robert W. Williams, Michael W. Pennington

Journal:

International Journal of Peptide Research and Therapeutics

Year:

1996

Language:

english

File:

PDF, 265 KB

english, 1996

17

Alzheimer's drug design based upon an invertebrate toxin (anabaseine) which is a potent nicotinic receptor agonist

Journal:

Invertebrate Neuroscience

Year:

1997

Language:

english

File:

PDF, 968 KB

english, 1997

18

DMXB, an α7nicotinic agonist, normalizes auditory gating in isolation-reared rats

Heidi C. O'Neill, Kate Rieger, William R. Kem, Karen E. Stevens

Journal:

Psychopharmacology

Year:

2003

Language:

english

File:

PDF, 269 KB

english, 2003

19

Alpha-7 nicotinic receptor agonists: potential new candidates for the treatment of schizophrenia

Laura F. Martin, William R. Kem, Robert Freedman

Journal:

Psychopharmacology

Year:

2004

Language:

english

File:

PDF, 173 KB

english, 2004

20

Nicotine analog inhibition of nicotine self-administration in rats

Neil E. Rowland, Kimberly Robertson, Ferenc Soti, William R. Kem

Journal:

Psychopharmacology

Year:

2008

Language:

english

File:

PDF, 181 KB

english, 2008

21

Selective α7-nicotinic agonists normalize inhibition of auditory response in DBA mice

Karen E. Stevens, William R. Kem, Vladimir M. Mahnir, Robert Freedman

Journal:

Psychopharmacology

Year:

1998

Language:

english

File:

PDF, 602 KB

english, 1998

22

Structure and membrane actions of a marine worm protein cytolysin, Cerebratulus toxin A-III

Journal:

Year:

1994

Language:

english

File:

PDF, 1.16 MB

english, 1994

23

Synthesis and conformational analysis of a bridged anabasine and related compounds. A nuclear magnetic resonance spectroscopy and molecular modeling study.

Katalin Prokai-Tatrai, John A. Zoltewicz, William R. Kem

Journal:

Year:

1994

Language:

english

File:

PDF, 735 KB

english, 1994

24

A new phospholipase A2 isolated from the sea anemone Urticina crassicornis – its primary structure and phylogenetic classification

Andrej Razpotnik, Igor Križaj, Jernej Šribar, Dušan Kordiš, Peter Maček, Robert Frangež, William R. Kem, Tom Turk

Journal:

Year:

2010

Language:

english

File:

PDF, 535 KB

english, 2010

25

Cloning and Evaluation of the Role of Rat GALR-2, a Novel Subtype of Galanin Receptor, in the Control of Pain Perception

SULTAN AHMAD, DAJAN O'DONNELL, KEM PAYZA, JULIE DUCHARME, DANIEL MÉNARD, WILLIAM BROWN, RALF SCHMIDT, CLAES WAHLESTEDT, S. H. SHEN, PHILIPPE WALKER

Journal:

Annals of the New York Academy of Sciences

Year:

1998

Language:

english

File:

PDF, 508 KB

english, 1998

26

Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal α7 nicotinic acetylcholine receptor

Hibbs, Ryan E, Sulzenbacher, Gerlind, Shi, Jianxin, Talley, Todd T, Conrod, Sandrine, Kem, William R, Taylor, Palmer, Marchot, Pascale, Bourne, Yves

Journal:

The EMBO Journal

Year:

2009

Language:

english

File:

PDF, 1.52 MB

english, 2009

27

Amphiporus alkaloid multiplicity implies functional diversity: initial studies on crustacean pyridyl receptors

William R. Kem, Ferenc Soti

Journal:

Year:

2001

Language:

english

File:

PDF, 472 KB

english, 2001

28

Sea anemone toxins as templates for the design of immunosuppressant drugs

William R. Kem, Michael W. Pennington, Raymond S. Norton

Journal:

Perspectives in Drug Discovery and Design

Year:

1999

Language:

english

File:

PDF, 123 KB

english, 1999

29

Structure and Action of Nemertine Toxins

KEM, WILLIAM R.

Journal:

Integrative and Comparative Biology

Year:

1985

Language:

english

File:

PDF, 850 KB

english, 1985

30

ChemInform Abstract: Racemic Synthesis of 2′-Substituted Nicotine Analogues

Anne Rouchaud, William R. Kem

Journal:

Year:

2012

File:

PDF, 31 KB

2012

31

Circular dichroism and laser Raman spectroscopic analysis of the secondary structure ofCerebratulus lacteustoxin B-IV

William R. Kem, Chiang-Kuang Tu, Robert W. Williams, Arazdordi Toumadje, W. Curtis Johnson

Journal:

The Protein Journal

Year:

1990

Language:

english

File:

PDF, 1008 KB

english, 1990

32

Improved learning and memory in aged rats with chronic administration of the nicotinic receptor agonist GTS-21

Gary W. Arendash, Gregory J. Sengstock, Paul R. Sanberg, William R. Kem

Journal:

Year:

1995

Language:

english

File:

PDF, 862 KB

english, 1995

33

Limited proteolysis study of structure-function relationships in Sh I, a polypeptide neurotoxin from a sea anemone

Stephen A. Monks, Alison R. Gould, Paul E. Lumley, Paul F. Alewood, William R. Kem, Neil H. Goss, Raymond S. Norton

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1994

Language:

english

File:

PDF, 778 KB

english, 1994

34

Synthesis and structural characterisation of analogues of the potassium channel blocker charybdotoxin

Timothy R. Dyke, Brendan M. Duggan, Michael W. Pennington, Michael E. Byrnes, William R. Kem, Raymond S. Norton

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1996

Language:

english

File:

PDF, 746 KB

english, 1996

35

Continuous administration of a selective α7 nicotinic partial agonist, DMXBA, improves sensory inhibition without causing tachyphylaxis or receptor upregulation in DBA/2 mice

Karen E. Stevens, Brandon Cornejo, Catherine E. Adams, Lijun Zheng, Joan Yonchek, Keith L. Hoffman, Uwe Christians, William R. Kem

Journal:

Year:

2010

Language:

english

File:

PDF, 500 KB

english, 2010

36

Relative toxicities and neuromuscular nicotinic receptor agonistic potencies of anabasine enantiomers and anabaseine

Stephen T. Lee, Kristin Wildeboer, Kip E. Panter, William R. Kem, Dale R. Gardner, Russell J. Molyneux, Cheng-Wei Tom Chang, Ferenc Soti, James A. Pfister

Journal:

Neurotoxicology and Teratology

Year:

2006

Language:

english

File:

PDF, 227 KB

english, 2006

37

Actions of piperidine alkaloid teratogens at fetal nicotinic acetylcholine receptors

Benedict T. Green, Stephen T. Lee, Kip E. Panter, Kevin D. Welch, Daniel Cook, James A. Pfister, William R. Kem

Journal:

Neurotoxicology and Teratology

Year:

2010

Language:

english

File:

PDF, 912 KB

english, 2010

38

63. Discovery of the Nicotinic Receptor Toxin Anabaseine in a Polystyliferan Nemertine

William R. Kem, Juan Junoy

Journal:

Year:

2012

Language:

english

File:

PDF, 59 KB

english, 2012

39

Inhibition of nitric oxide synthase prevents α7 nicotinic receptor-mediated restoration of inhibitory auditory gating in rat hippocampus

Catherine E Adams, Karen E Stevens, William R Kem, Robert Freedman

Journal:

Year:

2000

Language:

english

File:

PDF, 419 KB

english, 2000

40

GTS-21, A Mixed Nicotinic Receptor Agonist/Antagonist, Does Not Affect The Nicotine Cue

Frans Van Haaren, Karen G Anderson, Stephen C Haworth, William R Kem

Journal:

Pharmacology Biochemistry and Behavior

Year:

1999

Language:

english

File:

PDF, 106 KB

english, 1999

41

Chemical synthesis of a neurotoxic polypeptide from the sea anemone Stichodactyla helianthus

MICHAEL W. PENNINGTON, WILLIAM R. KEM, RAYMOND S. NORTON, BEN M. DUNN

Journal:

Chemical Biology & Drug Design

Year:

1990

Language:

english

File:

PDF, 854 KB

english, 1990

42

Quantitative structure-activity relationships for sea anemone polypeptide toxins

SVEN HELLBERG, WILLIAM R. KEM

Journal:

Chemical Biology & Drug Design

Year:

1990

Language:

english

File:

PDF, 448 KB

english, 1990

43

Synthesis of the cardiac inotropic polypeptide anthopleurin-A

MICHAEL W. PENNINGTON, INNA ZADENBERG, MICHAEL E. BYRNES, RAYMOND S. NORTON, WILLIAM R. KEM

Journal:

Chemical Biology & Drug Design

Year:

1994

Language:

english

File:

PDF, 665 KB

english, 1994

44

1H-NMR study of neurotoxin B-IV from the marine worm Cerebratulus lacteus : Solution properties, sequence-specific resonance assignments, secondary structure and global fold

Poul Erik HANSEN, William R. KEM, Allan L. BIEBER, Raymond S. NORTON

Journal:

Year:

1992

Language:

english

File:

PDF, 1.00 MB

english, 1992

45

[Progress in Molecular and Subcellular Biology] Marine Toxins as Research Tools Volume 46 || Ligands for Ionotropic Glutamate Receptors

Fusetani, Nobuhiro, Kem, William

Year:

2009

Language:

english

File:

PDF, 2.07 MB

english, 2009

46

Isolation, characterization, and amino acid sequence of a polypeptide neurotoxin occurring in the sea anemone Stichodactyla helianthus

Kem, William R., Parten, Benne, Pennington, Michael W., Price, David A., Dunn, Ben M.

Journal:

Year:

1989

Language:

english

File:

PDF, 870 KB

english, 1989

47

[Progress in Molecular and Subcellular Biology] Marine Toxins as Research Tools Volume 46 || Marine Toxins: An Overview

Fusetani, Nobuhiro, Kem, William

Year:

2009

File:

PDF, 1.62 MB

2009

48

Structure of neurotoxin B-IV from the marine Worm Cerebratulus lacteus: a helical hairpin cross-linked by disulphide bonding

Kevin J. Barnham, Timothy R. Dyke, William R. Kem, Raymond S. Norton

Journal:

Journal of Molecular Biology

Year:

1997

Language:

english

File:

PDF, 1.04 MB

english, 1997

49

Structure and action of heteronemertine polypeptide toxins: Inactivation of Cerebratulus lacteus toxin B-IV by tyrosine nitration

Kenneth M. Blumenthal, William R. Kem

Journal:

Archives of Biochemistry and Biophysics

Year:

1980

Language:

english

File:

PDF, 485 KB

english, 1980

50

Binding of a radiolabeled sea anemone cytolysin to erythrocyte membranes

James W. Doyle, William R. Kem

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1989

Language:

english

File:

PDF, 532 KB

english, 1989

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